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Neurobiology of Depression

Neurobiology of Depression

Detail Book : Neurobiology of Depression written by Francisco Lopez-Munoz, published by CRC Press which was released on 09 September 2011. Download Neurobiology of Depression Books now! Available in PDF, ePub and Kindle. Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology, and pharmacology, Neurobiology of Depression discusses the nature of the central nervous system circuits responsible for the modifications of neuronal functioning that lead to depression. The book begins by discussing animal, neurophysiological, and neuropsychological models of depression as well as neural foundations. It explores genetic factors that contribute to depression and describes the effect of monoaminergic systems in the central nervous system. Next, the book profiles the rise of psychopharmacology in the treatment of depression and the research into serotonin and monoamine reuptake inhibitors. It examines the role of the glutamatergic, endocannabinoid, and opioid systems in the pathophysiology of mood disorders, as well as the effect of biological rhythms on the human body. Later chapters review the role of CRF-related ligands, CRF receptors, HPA axis activity, and glucocorticoid receptors in the regulation of the stress response and depression. They also describe cytokine modulation of molecular mechanisms. They examine the role of neuropeptide Y, nitric oxide, beta-arrestins, BDNF, and phosphodiesterases, and discuss the use of tachykinin antagonists in treatment. Finally, they analyze the neurobiological basis for the development of new antidepressant agents. Exploring myriad aspects of a disease that plagues a large percentage of the population worldwide, this volume captures the state of the science of this debilitating disorder, facilitating further research and discovery.

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Author : Francisco Lopez-Munoz
Release Date : 09 September 2011
Publisher : CRC Press
Rating : 4/5 (from 21 users)
Pages : 522
ISBN : 1439838496
Format : PDF, ePUB, KF8, PDB, MOBI, Tuebl
Neurobiology of Depression

Neurobiology of Depression

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology,

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Systems Neuroscience in Depression

Systems Neuroscience in Depression

Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with

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Neurobiology of Depression

Neurobiology of Depression

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives

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The Neuroscience of Depression

The Neuroscience of Depression

The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book provides readers with the behavior and psychopathological effects of depression, linking anxiety, anger and PSTD to depression. Readers are provided with a detailed outline of

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The Upward Spiral

The Upward Spiral

Depression can feel like a downward spiral, pulling you into a vortex of sadness, fatigue, and apathy. In The Upward Spiral, neuroscientist Alex Korb demystifies the intricate brain processes that cause depression and offers a practical and effective approach to getting better. Based on the latest research in neuroscience, this

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The Upward Spiral Workbook

The Upward Spiral Workbook

Positive life changes lead to positive brain changes. Drawing on the huge success of his groundbreaking book, The Upward Spiral, neuroscientist Alex Korb offers actionable, step-by-step skills to help you reshape your brain and create an upward spiral towards a happier, healthier life. Depression is defined by a collection of

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Vulnerability to Depression

Vulnerability to Depression

Providing a cutting-edge examination of the mechanisms underlying depression, this volume integrates important areas of research that have largely remained separate. The authors explore both the cognitive and neurological processes that make some people more vulnerable than others to developing depression and experiencing recurrent episodes. They also probe how these

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Cognitive Affective Neuroscience of Depression and Anxiety Disorders

Cognitive Affective Neuroscience of Depression and Anxiety Disorders

Data on depression and anxiety disorders now spans a range of fields from molecular neuroscience, through cognitive and affective science, and on to evolutionary psychology. The author here integrates this work into one volume, providing the clinician with a theoretical synthesis as well as a useful practical framework. Cognitive-Affective Neuroscience

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Inflammation and Immunity in Depression

Inflammation and Immunity in Depression

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly

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The Inflamed Mind

The Inflamed Mind

As seen on "CBS This Morning" Worldwide, depression will be the single biggest cause of disability in the next twenty years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still...until now with Edward Bullmore's The

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Ketamine for Treatment Resistant Depression

Ketamine for Treatment Resistant Depression

Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. Provides efficacy research on ketamine as a treatment for depression Identifies best practices

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The Oxford Handbook of Mood Disorders

The Oxford Handbook of Mood Disorders

The most comprehensive volume of its kind, The Oxford Handbook of Mood Disorders provides detailed coverage of the characterization, understanding, and treatment of mood disorders. Chapters are written by the world's leading experts in their respective areas. The Handbook provides coverage of unipolar depression, bipolar disorder, and variants of these

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The End of Mental Illness

The End of Mental Illness

New hope for those suffering from conditions like depression, anxiety, bipolar disorder, addictions, PTSD, ADHD and more. Though incidence of these conditions is skyrocketing, for the past four decades standard treatment hasn't much changed, and success rates in treating them have barely improved, either. Meanwhile, the stigma of the "mental

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Major Depressive Disorder

Major Depressive Disorder

Major depressive disorder (MDD) is a complex and heterogeneous disorder, phenotypically and biologically. MDD may be caused by complex interaction between genes and environment in susceptible individuals. Thus, a combination of certain genetic polymorphism, environmental stress, and personal susceptibility ultimately may induce MDD. Gene-environment interactions in the pathophysiology of MDD

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Lifting Depression

Lifting Depression

Drawing on the latest findings from neuroscience, as well as cultural observation and her own unique laboratory research, psychologist Kelly Lambert puts forth a provocative new theory about the cause and treatment of depression. Today's young adults are up to ten times more likely to experience depression than their grandparents

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