Book > Polymer Protein Conjugates

Polymer Protein Conjugates

Polymer Protein Conjugates

Detail Book : Polymer Protein Conjugates written by Gianfranco Pasut, published by Elsevier which was released on 30 October 2019. Download Polymer Protein Conjugates Books now! Available in PDF, ePub and Kindle. Polymer–Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans. Provides an overview on the state-of-the-art of protein polymer conjugation Presents both the pros and cons of polymer-protein conjugates from the point-of-view of their clinical outcomes Outlines advantages and potential risks of present technology based on PEG Offers new alternatives for PEG and new approaches for on site-selective protein modification Identifies future direction of research in this field

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Author : Gianfranco Pasut
Release Date : 30 October 2019
Publisher : Elsevier
Rating : 4/5 (from 21 users)
Pages : 512
ISBN : 0444640827
Format : PDF, ePUB, KF8, PDB, MOBI, Tuebl
Polymer Protein Conjugates

Polymer Protein Conjugates

Polymer–Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers

GET BOOK
Polymer Protein Conjugates

Polymer Protein Conjugates

Polymer-Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design

GET BOOK
PEGylated Protein Drugs  Basic Science and Clinical Applications

PEGylated Protein Drugs Basic Science and Clinical Applications

PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the

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Bioconjugate Techniques

Bioconjugate Techniques

Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details

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Bio inspired Polymers

Bio inspired Polymers

Many key aspects of life are based on naturally occurring polymers, such as polysaccharides, proteins and DNA. Unsurprisingly, their molecular functionalities, macromolecular structures and material properties are providing inspiration for designing new polymeric materials with specific functions, for example, responsive, adaptive and self-healing materials. Bio-inspired Polymers covers all aspects of

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Protein based Engineered Nanostructures

Protein based Engineered Nanostructures

This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner

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Polymer Therapeutics II

Polymer Therapeutics II

With contributions by numerous experts

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Self Assembly

Self Assembly

An introduction to the state-of-the-art of the diverse self-assembly systems Self-Assembly: From Surfactants to Nanoparticles provides an effective entry for new researchers into this exciting field while also giving the state of the art assessment of the diverse self-assembling systems for those already engaged in this research. Over the last

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Polymer Therapeutics I

Polymer Therapeutics I

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Polymeric Nanomedicines

Polymeric Nanomedicines

Over the last few decades, numerous nanoparticle platforms have been studied for their use in therapeutic applications. This book deals with the description of the construction of technical systems that combines different functionalities which bring liposomes, polymer-drug conjugates, polymer-protein conjugates, dendrimers, polymeric micelles, polymerosomes and other nanoparticles into the realm

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Renewable Resources for Functional Polymers and Biomaterials

Renewable Resources for Functional Polymers and Biomaterials

This book details polysaccharides and other important biomacromolecules covering their source, production, structures, properties, and current and potential application in the fields of biotechnology and medicine. It includes a systematic discussion on the general strategies of isolation, separation and characterization of polysaccharides and proteins. Subsequent chapters are devoted to polysaccharides

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Bio synthetic Polymer Conjugates

Bio synthetic Polymer Conjugates

Polypeptide-Polymer Conjugates, by Henning Menzel Chemical Strategies for the Synthesis of Protein-Polymer Conjugates, by Björn Jung and Patrick Theato Glycopolymer Conjugates, by Ahmed M. Eissa and Neil R. Cameron DNA-Polymer Conjugates: From Synthesis, Through Complex Formation and Self-assembly to Applications, by Dawid Kedracki, Ilyès Safir, Nidhi Gour, Kien

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Thiol X Chemistries in Polymer and Materials Science

Thiol X Chemistries in Polymer and Materials Science

Thiol-X chemistries are already well established techniques, but it is only recently that they have been exploited for the functionalization and synthesis of polymers and other materials. As such, information on these techniques is scattered across the literature and Thiol-X Chemistries in Polymer and Materials Science is the first book

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Synthesis and Self assembly of Protein polymer Conjugates for the Preparation of Biocatalytically Active Membranes

Synthesis and Self assembly of Protein polymer Conjugates for the Preparation of Biocatalytically Active Membranes

This thesis covers the synthesis of conjugates of 2-Deoxy-D-ribose-5-phosphate aldolase (DERA) with suitable polymers and the subsequent immobilization of these conjugates in thin films via two different approaches. 2-Deoxy-D-ribose-5-phosphate aldolase (DERA) is a biocatalyst that is capable of converting acetaldehyde and a second aldehyde as acceptor into enantiomerically

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Silicon Versus Carbon

Silicon Versus Carbon

Even though there is no generally accepted definition of nanotechnologies to be defined as distinct discipline there is an emerging consensus that their advent and development is a growing in importance factor of the contemporary and future technological civilization. One of these most fundamental issues we are confronted with is

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