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Non Canonical Autophagy

Non Canonical Autophagy

Detail Book : Non Canonical Autophagy written by Lorenzo Galluzzi, published by Academic Press which was released on 01 May 2021. Download Non Canonical Autophagy Books now! Available in PDF, ePub and Kindle. Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. Non-canonical Autophagy: Mechanisms and Pathophysiological Implications also discusses all the forms ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death as the challenges and pitfalls in the development of clinically viable modulators of autophagy. This book aims to give readers a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret biological effects of autophagy correctly and identify reliable novel and effective treatment strategies. Presents the most advanced information regarding the molecular mechanism underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

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Author : Lorenzo Galluzzi
Release Date : 01 May 2021
Publisher : Academic Press
Rating : 4/5 (from 21 users)
Pages : 250
ISBN : 0128209119
Format : PDF, ePUB, KF8, PDB, MOBI, Tuebl
Non Canonical Autophagy

Non Canonical Autophagy

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. Non-canonical Autophagy: Mechanisms and Pathophysiological Implications also discusses all the forms ‘non-canonical’

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Regulation of B Cell Responses by Non canonical Autophagy

Regulation of B Cell Responses by Non canonical Autophagy

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Autophagy in Health and Disease

Autophagy in Health and Disease

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the

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Autophagy in Autoimmunity

Autophagy in Autoimmunity

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Autophagy of the Nervous System

Autophagy of the Nervous System

What is autophagy? Why would neurons or other brain cells digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as a culprit or accomplice to cell death in others? How does dysfunction of autophagy contribute to neurological diseases and can

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Non canonical Cyclic Nucleotides

Non canonical Cyclic Nucleotides

The cyclic purine nucleotides 3’,5’-cAMP and 3’,5’-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume 191). In addition to 3’,5’-cAMP and 3’,5’-cGMP, so-called non-canonical cyclic nucleotides exist. These comprise the cyclic pyrimidine nucleotides 3’,5’-cCMP and 3’,5’-cUMP, the purine nucleotide 3’,5’-cIMP,

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Autophagic Degradation of Organelles in the Yeast Saccharomyces Cerevisiae

Autophagic Degradation of Organelles in the Yeast Saccharomyces Cerevisiae

For some of the studies a fluorescent biosensor expressed in the cytosol, or targeted to mitochondria or the nucleus, was used in order to monitor autophagic degradation of the respective compartment/organelle. Here the assay was based upon a genetically encoded dual colour-emission biosensor. Rosella, the fusion of a relatively

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Protein Degradation

Protein Degradation

The first volume in a new series dedicated to protein degradation, this book lays the foundations of targeted protein breakdown via the ubiquitin pathway. The outstanding importance of the ubiquitin pathway has been recognized with the 2004 Nobel Prize in Chemistry for Aaaron Chiechanover, Avram Hershko, and Irwin Rose. Aaron Ciechanover

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Autophagy

Autophagy

Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied

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Autophagy in Current Trends in Cellular Physiology and Pathology

Autophagy in Current Trends in Cellular Physiology and Pathology

Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular

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Autophagy

Autophagy

This volume details a comprehensive and extensive set of protocols for the study of autophagy in vitro and in vivo. Chapters focus on mammals, various model organisms, and provide protocols for the study of autophagy-related processes outside of the canonical autophagy pathways. Written in the highly successful Methods in Molecular

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Membrane Biogenesis

Membrane Biogenesis

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins

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Induction of Central Nervous System Disease by the Adaptive Immune Response

Induction of Central Nervous System Disease by the Adaptive Immune Response

Over the last years it has become evident that many neurological diseases of the central nervous system (CNS) are induced by a specific adaptive immune response directed against molecules expressed on CNS-resident cells. Well-recognized examples are anti-N-Methyl-D-Aspartate Receptor (NMDAR) encephalitis which is characterized by the presence of antibodies against neuron-expressed

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Autophagy Networks in Inflammation

Autophagy Networks in Inflammation

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have

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