Book > Energy Metabolism In Heart Failure

Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease

Detail Book : Cardiac Energy Metabolism in Health and Disease written by Gary D. Lopaschuk, published by Springer which was released on 22 August 2014. Download Cardiac Energy Metabolism in Health and Disease Books now! Available in PDF, ePub and Kindle. The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

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Author : Gary D. Lopaschuk
Release Date : 22 August 2014
Publisher : Springer
Rating : 4/5 (from 21 users)
Pages : 295
ISBN : 1493912275
Format : PDF, ePUB, KF8, PDB, MOBI, Tuebl
Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease

The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change

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Novel Concepts in Cardiac Energy Metabolism  From Biology to Disease

Novel Concepts in Cardiac Energy Metabolism From Biology to Disease

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ATP and the Heart

ATP and the Heart

ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in our infancy applying what is known about biology and chemistry of ATP toward developing effective therapies for these diseases. In this volume, the current

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The Scientist s Guide to Cardiac Metabolism

The Scientist s Guide to Cardiac Metabolism

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of

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Mitochondrial Diseases

Mitochondrial Diseases

Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and

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The Failing Heart

The Failing Heart

(Proc./Intl Conf. 5/94) Topics inc. atrial defibrillation & congestive heart failure trmt of symptomatic heart failure.

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The Sinatra Solution

The Sinatra Solution

A board-certified cardiologist discusses the importance of energy metabolism on cardiovascular health and the positive impact three energy-supplying nutrients--CoQ10, Carnitine, and Ribose--have on the cardiovascular system.

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Myocardial Energy Metabolism

Myocardial Energy Metabolism

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Novel Concepts in Cardiac Energy Metabolism  From Biology to Disease

Novel Concepts in Cardiac Energy Metabolism From Biology to Disease

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Oxford Textbook of Heart Failure

Oxford Textbook of Heart Failure

The Oxford Textbook of Heart Failure takes the reader from an understanding of the basic mechanisms of heart failure, through to an appreciation of the complexities of heart failure management and the improvements possible with good treatment. Written by internationally renowned leaders in the field, this definitive textbook comprehensively covers

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Post Genomic Cardiology

Post Genomic Cardiology

Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of

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Heart Failure  A Companion to Braunwald s Heart Disease E Book

Heart Failure A Companion to Braunwald s Heart Disease E Book

Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald’s Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (

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Heart Failure  A Companion to Braunwald s Heart Disease E book

Heart Failure A Companion to Braunwald s Heart Disease E book

Dr. Douglas L. Mann, one of the foremost experts in the field, presents the 2nd Edition of Heart Failure: A Companion to Braunwald’s Heart Disease. This completely reworked edition covers the scientific and clinical guidance you need to effectively manage your patients and captures the dramatic advances made in

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Acute Heart Failure

Acute Heart Failure

For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first

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Cellular and Molecular Pathobiology of Cardiovascular Disease

Cellular and Molecular Pathobiology of Cardiovascular Disease

Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in

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